K9 EPILEPSY CLINICAL TRIALS & STUDIES

 

 
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If you are interested in participating in this study, please complete the pre-screening application
 
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NCSU-College of Veterinary Medicine Hosting Clinical Trials for Dogs With Idiopathic Epilepsy.
 
(click on image to read specs)

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***UPDATE: THIS GUT DYSBIOSIS/EPILEPSY STUDY CALL-OUT IS NOW CLOSED, WITH RESULTS TO HOPEFULLY BE ADDED BY LATE FALL/EARLY SPRING 2023/2024.***

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WHAT WAS THIS STUDY ABOUT? Dr. Muñana was “very actively recruiting” for this study, which is a new clinical trial, sponsored by the AKC-Canine Health Foundation, to “determine whether dogs with idiopathic epilepsy have alterations in their gut microbial population.” The study team at NCSU-CVM had a call-out (which we previously announced) “looking for households with an epileptic dog and an unaffected dog to compare the bacterial populations within their gastrointestinal tract." Feces were collected from both dogs to compare their gut microbiome. Samples had to be sent to NCSU-CVM (pre-paid shipping).

For information, contact: 

Julie Nettifee, RVT, BS, VTS (Neurology) at: janettif@ncsu.edu

 

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AKC-Canine Health Foumdation Sponsored Study Evaluationg Functional MRI in Drug-Naïve Dogs. 

 

For more information, contact: 

Julie Nettifee, RVT, BS, VTS (Neurology) at: janettif@ncsu.edu

 

 
 
Colorado State University Clinical Trials
Efficacy of Cannabidiol for the Treatment of Epilepsy in Dogs 

"Enrollment is still open! Over the past month we had four patients finish the trial and are continuing to enroll more dogs. In this trial we are evaluating the use of CBD as an add-on medication for the treatment of drug-resistant epilepsy. Idiopathic epilepsy is a general term for any epilepsy that develops in young to middle-aged dogs without any evidence of structural abnormalities in the brain or systemic signs of disease. Approximately 20-30% of dogs with idiopathic epilepsy are resistant to multiple anticonvulsants. In humans, CBD has been shown to be an effective anticonvulsant in the treatment of two childhood epileptic diseases (Lennox Gastaut and Dravet Syndrome); our hope is that this can be an effective treatment for epilepsy in dogs."

A Dose Finding Study of Cannabidiol in Dogs with Intractable Epilepsy

Background and purpose of the trial:

"Epilepsy is currently reported to affect approximately 5% of the canine population; of that number approximately 30% of dogs are poorly controlled on routine anti-epileptic drugs (AEDs). Recent CBD research has demonstrated the anti-convulsive properties in both canine and human patients; however, to-date a dose finding study has not been performed in veterinary patients. For the initial phase of this study, our primary purpose is to determine a dose of CBD that will reduce the seizure frequency in canine patients to 50% or less."


FOR MORE INFO, visit the website HERE, or contact one of their research technicians by Emailing CSUNeuroTrials@colostate.edu or by calling (970) 305-0455.

To download their brochure, visit HERE.
 

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